SPDP
- SMILES: O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O
- Formula: C12H12N2O4S2
- Purity: 1
- CAS#: 68181-17-9
- Molecular Weight: 312.36
- Bioactivity: SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could activate equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline
- pH 8.5).
For research use only.
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