Losartan Carboxylic Acid
- SMILES: CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1
- Formula: C22H21ClN6O2
- Purity: 0.9928
- CAS#: 124750-92-1
- Molecular Weight: 436.9
- Bioactivity: EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat
- 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, is more potent than losartan in blocking the angiotensin II-induced responses in vascular smooth muscle cells.
For research use only.
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