Quantitative sandwich ELISA for measuring Canine Transforming growth factor Beta1 (TGF-Beta1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
TGF-? is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-?1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-? is secreted by cells in the form of an inactive complex. This complex consists of TGF-?1 associated non-covalently with a protein designated the latency associated peptide (LAP).
TGF-?1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-?1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-?1 inactive and inaccessible to anti-TGF-? antibodies.
All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
- Reactivity: Dog
- Sample types: serum, whole blood, plasma and other biological fluids
- Detection range: Please inquire
- Sensitivity: Please inquire Quantitative Sandwich ELISA
- Method of detection: Colorimetric
This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.
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