Recombinant fusion protein containing a sequence corresponding to amino acids 66-394 of human ALKBH5 (NP_060228.3).
- Enables mRNA N6-methyladenosine dioxygenase activity. Involved in RNA metabolic process
- mRNA export from nucleus
- and response to hypoxia. Located in Golgi apparatus
- cytosol
- and nuclear speck.ALKBH5, also named as ABH5 and OFOXD1, is a Dioxygenase that demethylates RNA by oxidative demethylation. It is a mammalian demethylase that oxidatively reverses m6A in mRNA in vitro and in vivo. ALKBH5 is required for spermatogenesis.
Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Monoclonal Antibodies
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