FasL is a cytokine that binds to Fas/TNFRSF6, a receptor that transduces the apoptotic signal into cells. FasL is involved in cytotoxic T cell mediated apoptosis and in T cell development.
Stable for at least 6 months after receipt when stored at -20°C.
- Tested Applications: N/A
- Applications: This recombinant proteins is for research use only.
- Predicted Molecular Weight: N/A
- Physical state: Lyophilized
- Buffer: Contains PBS. Reconstitute with 50 µl sterile water.
- Concentration: 1mg/ml after reconstitution.
- NCBI official symbol: FAS
- Accession #: P25445
- Protein GI: 4507583
- NCBI gene ID#: 355
- NCBI official full name: Fas cell surface death receptor
- NCBI organism: Homo sapiens
- Peptide sequence: N/A
- SWISSPROT #: Q9QYY1
- Background Reference 1: N/A
- Background Reference 2: N/A
- Background Reference 3: N/A
- Background Reference 4: N/A
- Background Reference 5: N/A
- Source: HEK293 cells
- Species: Human, Mouse
- By Source: Human Cells
- By Species: Human, Mouse
- Fusion tag: Fc Tag
- Sequence: The Fc portion of human IgG1 is fused to the C-terminus of human Fas (aa 26-170).
- Biology activity: Blocks the binding of FasL to Fas.
- Purity: >95% (SDS-PAGE).
- Endotoxin level is less than 0.01EU/ µg purified protein (LAL test
- Lonza).
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
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