Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
- Clonality: Polyclonal
- Host: Rabbit
- Conjugation: Unconjugated
- Applications: WB,IF
- Reactivity: Human,Mouse
- Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Purification: Affinity purification
- Clone: NA
- Concentration: NA
- Gene: TALDO1
- Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-337 of human TALDO1 (NP_006746.1).
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