IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant murine IL-15 is a 13.3 kDa protein consisting of 115 amino acid residues.
- Gene name: IL-15
- Host: Rat
- Label: None
- Clone: (#15B9)
- Isotype: IgG2
- Applications: WB
- Species Reactivity/Origin species: Mouse
- Antigen: recombinant mouse protein of IL-15
- Purification method: Protein A/G chromatography
- Reconstitution Buffer: PBS
- Buffer: PBS
- Additives/Stabilizer: None
- Form: lyophilized
- Storage: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
- Reconstitution tips: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- NCBI GeneID: 16168
- Accession Number Protein: NP_032383.1
- Accession Numberm RNA: NM_008357
- Uniprot: P48346
- Chromosomal location: 8 C2
- 8 38.0 cM
For research use only.
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