Biomolecule/Target: 4-1BBL
Alternates names: TNFSF9, CD137L
Synonyms: TNFSF9, CD137L
Country of Animal Origin: USA
NCBI Gene ID: 8744
NCBI Gene Symbol: TNFL9
Gene Source: Human
Accession: P41273
Recombinant: Yes
Source: E. coli
Purity Determined by SDS-PAGE: >=98%
Purity Determined by HPLC: N/A
Endotoxin Level: <0.1 ng/ug Activity (Specifications/test method): N/A
Biological acivity: Determined by the dose-dependent stimulation of IL-8 production by human PBMC. The ED50 for the effect is less than 10 ng/ml. Please note: results may Vary with PBMC donors.
Results: 10 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 19.5 kDa
Storage Temperature: -20 Celsius
Shipping: Gel pack
Shelf Life: 12 months
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized from 5 mM Tris, pH 8.0 + 75 mM NaCl.
Reconstitution Instructions: We recommend a quick spin followed by reconstitution in H2O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 Celsius for 1 week or –20 Celsius for future use.
Background Information: Human 4-1BB Ligand (4-1BBL) is a member of the emerging family of Ligands with structural homology to tumor necrosis factor. Recombinant human 4-1BBL is a 19.5 kDa protein containing 185 amino acid residues, comprising the TNF-like extra-Cellular domain of 4-1BBL.
Amino acid sequence: N/A
Handling: In order to retain the quality of the proteins, please, aVoid cycles of freezing and thawing. For proteins that are in liquid form or reconstituted lyophilized proteins small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the Vial to gather all the solution on the bottom.
Usage: For Research Use Only! Not to be used in humans
Product type:
For more information, please, refer to the full datasheet.
