ZWINT Primary Polyclonal Antibody

Product Quantity: 0.1ml Manufacturer: BIOSS

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ZWINT Antibody

Short Name: Anti-ZWINT

Long Name: ZWINT Primary Polyclonal Antibody

Alternative Name: ZWINT Polyclonal Antibody

Synonym Names: HZwint1; KNTC 2 AP; KNTC2AP; MGC 117174; MGC117174; ZW10 interacting protein 1; ZW10 interactor; ZWINT 1; ZWINT1; ZWINT-1; ZWINT_HUMAN.

Also Known As: ZWINT PAb

Conjugation: Unconjugated

Host: Rabbit (Oryctolagus cuniculus)

Target Antigen: ZWINT

Specificity: This is a highly specific antibody against ZWINT.

Modifications: None

Modification Sites: Unmodified antibody

Clone number: Polyclonal antibody

Isotype: Immunoglobulin G (IgG)

Concentration: 1ug per 1ul

Immunogen range: 

Subcellular location: 

Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ZWINT

Gene ID number: 11130

Swiss Prot: 

Tested Applications: WB, IHC-P, IF(IHC-P)

Recommended dilutions: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Cross reactivity: Human, Mouse, Rat

Cross reactive species details: Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Background of the target antigen: ZWINT is a component of the MIS12 complex, which is required for kinetochore function and spindle checkpoint activity. ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase. ZWINT is detectable on the kinetochore till late anaphase. Inhibition of ZWINT expression results in chromosome missegregation, spindle checkpoint failure and, ultimately, cell death upon cytokinesis.

Purification method: This antibody was purified via Protein A.

Storage conditions: Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20шC for up to 1 year.