uPAR Antibody

Product Quantity: 100 ug Manufacturer: Biovision

448.25 £

Antibody Target: uPAR

Target Alternative Name: Urokinase plasminogen activator receptor , PLAUR , uPAR , CD87 , MO3 , UPAR , URKR, Urokinase plasminogen activator surface receptor; U-PAR; uPAR; Monocyte activation antigen Mo3; CD_antigen, CD87

Tagline: 

Category: uPAR

Host: Goat

Antibody Type: Polyclonal

Isotype: Goat IgG

Clone: 

Species Reactivity: Human

Immunogen Sequence: E. coli expressed recombinant human uPAR

Accession: Q03405

Gene ID: 5329

Appearance: Colorless liquid

Antibody Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 ug (0.5 mg/ml) purified goat polyclonal antibody in 1X phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal..

Purification: Affinity purified

Application: Western blot, Immunoprecipitation, Neutralization

Positive Control: 

Application & Usage: Western blotting (0.5-2 ug/ml), immunoprecipitation (5-10 ug/ml), and neutralization (2-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 55 kDa human uPAR. Reactivity to other species has not been tested.

Background Descriptions: uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.

Storage Temperature: -20 Celsius

Shipping: gel pack

Shelf Life: 12 months

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use. Lyophilized and liquid form antibodies can be shipped and stored for short terms at +4 degrees Celsius and at -20 for long term storage.

Elisa: Not Verified

Western Blot (WB): Verified

Immunoprecipitation (IP): Not Verified

Immunofluorescence (IF): Not Verified

Flow Cytometry: Not Verified

Immunohistochemistry (IHC): Not Verified

Dot blot: 

ChIP: 

For more information, please, refer to the full datasheet.