The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses as well as protective immunity.
Store the lyophilized protein at -20°C to -20°C for long term. After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week
- Tested Applications: E, WB
- Applications: This recombinant protein can be used for WB, ELISA. For research use only.
- Predicted Molecular Weight: 77.7 kDa
- Physical state: Lyophilized
- Buffer: PBS, pH 7.4
- Concentration: N/A
- NCBI official symbol: S
- Accession #: YP_009724390.1
- Protein GI: N/A
- NCBI gene ID#: 43740568
- NCBI official full name: surface glycoprotein
- NCBI organism: Severe acute respiratory syndrome coronavirus 2
- Peptide sequence: Gln14-Arg683
- SWISSPROT #: P0DTC2
- Background Reference 1: N/A
- Background Reference 2: N/A
- Background Reference 3: N/A
- Background Reference 4: N/A
- Background Reference 5: N/A
- Source: HEK293 cells
- Species: SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein
- By Source: Human Cells
- By Species: Other
- Fusion tag: His tag and Avi at C-terminus
- Sequence: Gln14-Arg683
- Biology activity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant 2019-nCoV Spike S1-His at 2µg/mL (100 µL/well) can bind Recombinant Human ACE2 with a linear range of 1.5-15 ng/mL.
- Purity: > 95% by SDS-PAGE.
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