Roxadustat is an orally active hypoxia-inducible factor (HIF) prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin[1].
- -20°C, 3 years
- 4°C, 2 years (Powder)
- CAS number: 808118-40-3
- Purity: 99.91
- Formula: C19H16N2O5
- Solubility: DMSO : ≥ 100 mg/mL
- SMILES: O=C(O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)=O
- Molecular Weight: 352.34
- Applications: Cancer-programmed cell death
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