IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.
Store in -20°c for long term storage. After reconstitution, store in 4°c for short term usage within a few days. Avoid freeze-thaw cycles.
- category: Recombinant Proteins
- gene name: Il15
- contents: Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
- uniprot_id: P97604
- form: Solid
- white powder or thin/invisible film
- purification: NA
- applications: Cell Culture
- subcellular_localization: Secreted.
- source: E. Coli
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