PRE-GMP rHu GM-CSF, Molgramostim-Leukoma

Supplier: Gentaur

0.01 GBP
Catalog: 10-04-RHUGM-CSF-7A10 Stock:On request
Product Size: 300 µg

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What is PRE-GMP rHu GM-CSF, Molgramostim-Leukoma ?

PRE-GMP rHu GM-CSF, Molgramostim-Leukoma is a monomer glycoprotein secreted by macrophages that is often used in the laboratory.

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PRE-GMP rHu GM-CSF, Molgramostim-Leukoma

PRE-GMP rHu GM-CSF, Molgramostim-Leukoma

PRE-GMP rHu GM-CSF, Molgramostim-Leukoma , Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T lymphocytes, mast cells, NK cells, endothelial cells and fibroblasts, which functions as a cytokine. Pharmaceutical analogues of natural GM-CSF are called sargramostim and molgramostim. It is recommended that a sterile ddH2O stock solution containing at least 0.1% human or bovine serum albumin be added to the vial to prepare a stock solution of at least 1 mg/ml cytokine.


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A substance that helps to produce more white blood cells, in particular granulocytes, macrophages and cells that become platelets. It is a cytokine that is a type of haematopoietic (blood-forming) agent. It is also called granulocyte-macrophage colony-stimulating factor and sargramostim.

GM-CSF is a haematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of erythroid, megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T lymphocytes. GM-CSF inhibits the migration of neutrophils and enhances the functional activity of mature terminal cells. The human and murine molecules are species-specific and show no interspecific reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein composed of 128 amino acids, containing two intramolecular disulphide bonds and two potential N-linked glycosylation sites.

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