PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Store the PDL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Human
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