NOD4 Antibody

Supplier: Gentaur

0.01 GBP
Catalog: 223-5951-002mg Stock:On request
Product Size: 0.02 mg

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NOD4 Antibody: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-κB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.



Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.


  • NOD4 antibody can be stored at 4˚
  • C for three months and -20˚
  • C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.


  • Research area: Innate Immunity
  • Host species: Rabbit
  • Species reactivity: Human, Mouse
  • Homology: N/A
  • Immunogen: NOD4 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NOD4.
  • The immunogen is located within amino acids 20 - 70 of NOD4.
  • Tested Applications: E, WB, ICC, IF
  • Applications: NOD4 antibody can be used for detection of NOD4 by Western blot at 1 μ
  • g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ
  • g/mL. For immunofluorescence start at 20 μ
  • g/mL.
  • Antibody validated: Western Blot in mouse samples
  • Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
  • Specificity: NOD4 antibody is predicted to not cross-react with other members of the NOD family of proteins.
  • Positive control 1: Cat. No. 1287 - EL4 Cell Lysate
  • Positive control 2: Cat. No. 17-001 - HeLa Cell Slide
  • Positive control 3: N/A
  • Positive control 4: N/A
  • Positive control 5: N/A
  • Positive control 6: N/A
  • Predicted molecular weight: 205 kDa
  • MW explanation: N/A
  • Validation: N/A
  • Isoforms: N/A
  • Purification: NOD4 Antibody is affinity chromatography purified via peptide column.
  • Clonality: Polyclonal
  • Clone: N/A
  • Isotype: IgG
  • Conjugate: Unconjugated
  • Physical state: Liquid
  • Buffer: NOD4 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Concentration: 1 mg/mL
  • NCBI official symbol: NLRC5
  • Accession #: NP_115582
  • Protein GI #: 116268109
  • NCBI gene ID#: 84166
  • NCBI official full name: NLR family, CARD domain containing 5
  • NCBI organism: Homo sapiens
  • SWISSPROT #: Q86WI3

Optimal dilutions for each application to be determined by the researcher.

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