A monoclonal antibody from clone S74-25 against Human TrpM7. The host species for the production of this antibody is Mouse. The antigen used for immunization is Mouse Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7. The antibody is tested and validated for WB (for use in transiently transfected cells only), IHC, ICC/IF, AM assays with the following recommended dilutions: WB (1:1000), IHC (1:1000), ICC/IF (1:100). This MAb for TrpM7 is conjugated with Dylight 633.
TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants (1, 2).
- Shipped on ice packs at +4ºC . Upon receiving the antibody store it at -20ºC.
- The gross weight of the package is 1.4 kg. and the net weight of the product is 0.1 grams.
- The item is not hazardous according to both ADR and UN. Its tariff code is 3002.15.0000 (Immunological products, put up in measured doses or in forms or packings for retail sale). The UNSPSC code of the product is 12352203 (Antibodies).
This product is not for human or animal treatment or consumption. Not for use in diagnostics or therapeutics. For in vitro research use only.
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