After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. [RefSeq]
IHC-P
Store the Insulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Human, Mouse, Rat
0 reviews for NSJ Bioreagents