DR4 Antibody

Product Quantity: 100 ug Manufacturer: Biovision

380.75 £

Antibody Target: DR4

Target Alternative Name: TNFRSF10A, TRAILR1, MGC9365, APO2, CD261, TRAIL-R1, TRAILR-1

Tagline: 

Category: DR4

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Clone: 

Species Reactivity: Mouse

Immunogen Sequence: Synthetic peptide corresponding to residues surrounding amino acids 454 of human DR4

Accession: O00220

Gene ID: 8797

Appearance: Colorless liquid

Antibody Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 ug (0.5 mg/ml) affinity purified rabbit anti-DR4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application: Western blot

Positive Control: 

Application & Usage: Western blot analysis (0.5-4 ug/ml) and immunofluorescence. However, the optimal conditions should be determined individually. The antibody detects a 57 kDa mouse DR4 in Western blot analysis.

Background Descriptions: Apoptosis can be induced by certain cytokines including TNF and Fas Ligand of the TNF super-family through their death domain (DD) containing receptors, TNFR1 and Fas. A member of the TNF receptor family was recently identified and designated DR4 (death receptor 4) and TRAIL-R1. The ligand for this novel death receptor has been identified and termed TRAIL. DR4 is expressed in most of the human tissues including spleen, peripheral blood leukocytes (PBLs), small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NFkB activation in many tissues and cells.

Storage Temperature: -20 Celsius

Shipping: gel pack

Shelf Life: 12 months

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use. Lyophilized and liquid form antibodies can be shipped and stored for short terms at +4 degrees Celsius and at -20 for long term storage.

Elisa: Not Verified

Western Blot (WB): Verified

Immunoprecipitation (IP): Not Verified

Immunofluorescence (IF): Not Verified

Flow Cytometry: Not Verified

Immunohistochemistry (IHC): Not Verified

Dot blot: 

ChIP: 

For more information, please, refer to the full datasheet.