Description of target: May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R.2 Publications
<p>Manually curated information for which there is published experimental evidence.</p>
<p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.1"A cellular repressor of E1A-stimulated genes that inhibits activation by E2F."_x005F_x005F_x000D_Veal E., Eisenstein M., Tseng Z.H., Gill G._x005F_x005F_x000D_Mol. Cell. Biol. 18:5032-5041(1998) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION.Ref.9"The secreted glycoprotein CREG inhibits cell growth dependent on the mannose-6-phosphate/insulin-like growth factor II receptor."_x005F_x005F_x000D_Di Bacco A., Gill G._x005F_x005F_x000D_Oncogene 22:5436-5445(2003) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH IGF2R, FUNCTION. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.113 ng/mL
CREG1 ELISA Kit (Human) (OKCD01089)
Aviva Systems BiologySupplier: Gentaur
Catalog: 247-OKCD01089
Stock:On request
Product Size: 96 Wells
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