Calreticulin Antibody (Clone S75)

Product Quantity: 100 ug Manufacturer: Biovision

448.25 £

Antibody Target: Calreticulin

Target Alternative Name: CRP55, CRTC, CALR, Calregulin, cC1qR, ERp60, HACBP, RO, SSA,

Tagline: 

Category: Calrecticulin

Host: Mouse

Antibody Type: Monoclonal

Isotype: Mouse IgG1

Clone: S75

Species Reactivity: Human, mouse, rat

Immunogen Sequence: Calreticulin-Maltose binding fusion protein

Accession: P27797

Gene ID: 811

Appearance: Colorless liquid

Antibody Form: Liquid

Concentration: 0.2 mg/ml

Formulation: 100 ug (200 ug/ml) protein A purified antibody in PBS containing 30% glycerol, 0.5 mg/ml BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application: Western blot, Immunohistochemistry

Positive Control: 

Application & Usage: Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Other applications have not been tested.

Background Descriptions: Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies suggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also suggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites.

Storage Temperature: -20 Celsius

Shipping: gel pack

Shelf Life: 12 months

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use. Lyophilized and liquid form antibodies can be shipped and stored for short terms at +4 degrees Celsius and at -20 for long term storage.

Elisa: Not Verified

Western Blot (WB): Verified

Immunoprecipitation (IP): Not Verified

Immunofluorescence (IF): Not Verified

Flow Cytometry: Not Verified

Immunohistochemistry (IHC): Not Verified

Dot blot: 

ChIP: 

For more information, please, refer to the full datasheet.