Bax Antibody

Product Quantity: 100 ug Manufacturer: Biovision

380.75 £

Antibody Target: Bax

Target Alternative Name: 581, BAX, 600040, P55269, Bax zeta

Tagline: 

Category: Bcl-2

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Clone: 

Species Reactivity: Human, mouse, rat, monkey

Immunogen Sequence: Synthetic peptide corresponding to amino acids near the N-terminus of human Bax

Accession: L22473

Gene ID: 581

Appearance: Colorless liquid

Antibody Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 ug (0.5 mg/ml) affinity purified rabbit anti-Bax polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application: Western blot, Immunoprecipitation

Positive Control: 

Application & Usage: Western blot analysis (0.5-4 ug/ml), immunoprecipitation (10-20 ug/ml). However, the optimal conditions should be determined individually.The antibody detects a 20 kDa protein, corresponding to the apparent molecular weight of Bax on SDS-PAGE immunoblots.

Background Descriptions: The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bak) apoptosis. Bax contains the conserved Bcl-2 homology 1 (BH1) and 2 (BH2) domains that allow for its homodimerization or heterodimerization with Bcl-2. When Bcl-2 is in excess, apoptosis is inhibited. However, if Bax levels increase in response to a death signal, the cell is pushed toward death.

Storage Temperature: -20 Celsius

Shipping: gel pack

Shelf Life: 12 months

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use. Lyophilized and liquid form antibodies can be shipped and stored for short terms at +4 degrees Celsius and at -20 for long term storage.

Elisa: Not Verified

Western Blot (WB): Verified

Immunoprecipitation (IP): Not Verified

Immunofluorescence (IF): Not Verified

Flow Cytometry: Not Verified

Immunohistochemistry (IHC): Not Verified

Dot blot: 

ChIP: 

For more information, please, refer to the full datasheet.