Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
In 1X PBS, pH 7.4, with 0.09% sodium azide
Aliquot the BACE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Human, Mouse
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