Anti-CD207 antibody (Alexa-fluor 546)

St John's Laboratory

353.70 £

Product ID: STJ170015

In stock

Size: 100 µg

Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

  • Clonality: Monoclonal
  • Host: Mouse
  • Conjugation: Alexa-fluor 546
  • Applications: IF
  • Reactivity: NA
  • Formulation: PBS 50% glycerol
  • Purification: QMA Hyper D ion exchange chromatography
  • Clone: 0
  • Concentration: 0.5 mg/ml
  • Gene: CD207
  • Immunogen: In vitro-derived human DCs from CD34+ cells in GM-CSF+TNFa

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