AMPKalpha2 Antibody

Product Quantity: 100 ug Manufacturer: Biovision

488.75 £

Antibody Target: AMPKalpha2

Target Alternative Name: EC 2.7.11.1, AMPK alpha-2 chain

Tagline: 

Category: AMPK

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Clone: 

Species Reactivity: Human, mouse

Immunogen Sequence: Synthetic peptide selected from the C-terminal region of human PRKAA2

Accession: P54646

Gene ID: 5563

Appearance: Colorless liquid

Antibody Form: Liquid

Concentration: 0.25 mg/ml

Formulation: 100 ug (0.25 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Purification: Affinity purified

Application: ELISA, Western blot, Immunohistochemistry

Positive Control: 

Application & Usage: The antibody can be used for ELISA (0.25 ug/ml), Western blotting (2.5 – 5.0 ug/ml) and Immunohistochemistry (5 – 25 ug/ml).

Background Descriptions: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Storage Temperature: -20 Celsius

Shipping: gel pack

Shelf Life: 12 months

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use. Lyophilized and liquid form antibodies can be shipped and stored for short terms at +4 degrees Celsius and at -20 for long term storage.

Elisa: Verified

Western Blot (WB): Verified

Immunoprecipitation (IP): Not Verified

Immunofluorescence (IF): Not Verified

Flow Cytometry: Not Verified

Immunohistochemistry (IHC): Verified

Dot blot: 

ChIP: 

For more information, please, refer to the full datasheet.