Biomolecule/Target: 4-1BB Receptor
Alternates names: TNFRSF9, CD137 antigen, T-cell antigen ILA
Synonyms: TNFRSF9, CD137 antigen, T-cell antigen ILA
Country of Animal Origin: USA
NCBI Gene ID: 3604
NCBI Gene Symbol: TNR9
Gene Source: Human
Source: E. coli
Purity Determined by SDS-PAGE: >=98%
Purity Determined by HPLC: >=98%
Endotoxin Level: <0.1 ng/ug Activity (Specifications/test method): N/A
Biological acivity: Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC. About 90% of inhibition was seen using a concentration of 1 ug for both 4-1BBL and 4-1BBR.
Results: 1 ug
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 17.8 kDa
Storage Temperature: -20 Celsius
Shipping: Gel pack
Shelf Life: 12 months
Appearance: Lyophilized protein
Physical form description: Lyophilized with no additIVes
Reconstitution Instructions: Reconstitute in H2O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 Celsius for 1 week or –20 Celsius for future use.
Background Information: Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactIVity. Recombinant human 4-1BBR is a 17.8 kDa protein containing 167 amino acid residues of extraCellular domain of 4-1BBR without signal peptide (Gene accession # NP_001552).
Amino acid sequence: N/A
Handling: In order to retain the quality of the proteins, please, aVoid cycles of freezing and thawing. For proteins that are in liquid form or reconstituted lyophilized proteins small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the Vial to gather all the solution on the bottom.
Usage: For Research Use Only! Not to be used in humans
For more information, please, refer to the full datasheet.